Go to content
UR Home

CRISPR-Cas9 Mediated TSPO Gene Knockout alters Respiration and Cellular Metabolism in Human Primary Microglia Cells

URN to cite this document:
DOI to cite this document:
Milenkovic, Vladimir M. ; Slim, Dounia ; Bader, Stefanie ; Koch, Victoria ; Heinl, Elena-Sofia ; Alvarez-Carbonell, David ; Nothdurfter, Caroline ; Rupprecht, Rainer ; Wetzel, Christian H.
Date of publication of this fulltext: 23 Jul 2019 12:47


The 18 kDa translocator protein (TSPO) is an evolutionary conserved cholesterol binding protein localized in the outer mitochondrial membrane. It has been implicated in the regulation of various cellular processes including oxidative stress, proliferation, apoptosis, and steroid hormone biosynthesis. Since the expression of TSPO in activated microglia is upregulated in various neuroinflammatory ...


Owner only: item control page
  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons