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Topical Diclofenac Reprograms Metabolism and Immune Cell Infiltration in Actinic Keratosis

Singer, Katrin, Dettmer, Katja, Unger, Petra, Schönhammer, Gabriele, Renner, Kathrin, Peter, Katrin, Siska, Peter J., Berneburg, Mark, Herr, Wolfgang, Oefner, Peter J., Karrer, Sigrid, Kreutz, Marina and Datz, Elisabeth (2019) Topical Diclofenac Reprograms Metabolism and Immune Cell Infiltration in Actinic Keratosis. Frontiers in Oncology 2019 (9), p. 605.

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Date of publication of this fulltext: 24 Jul 2019 06:25

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Other URL: http://doi.org/10.3389/fonc.2019.00605


Abstract

Background: Melanoma and squamous cell carcinoma of the skin are characterized by an altered glucose metabolism, but little is known about metabolic changes in precancerous skin lesions such as actinic keratosis (AK). Here, we studied the central carbon metabolism and immune cell infiltrate of actinic keratosis lesions before, under, and 4 weeks after treatment with topical diclofenac ...

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Item type:Article
Date:3 July 2019
Institutions:Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie)
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.3389/fonc.2019.00605DOI
Keywords:actinic keratosis, diclofenac, CD8, CD1a, metabolism, lactate
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:40562
Owner only: item control page

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