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The Drosophila Nephrocyte - Modeling Podocyte Function and Disease

Hochapfel, Florian (2019) The Drosophila Nephrocyte - Modeling Podocyte Function and Disease. PhD, Universität Regensburg.

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 22 Aug 2019 11:27

Abstract (English)

In modern industrialized nations, chronic non-communicable diseases have become the main reason of mortality. During the last years, the global health burden of chronic kidney diseases (CKD) has grown considerably and in many of these cases, no targeted or personalized therapies are available. To keep up with the rising challenges, the understanding of the causes and mechanisms underlying CKD ...


Translation of the abstract (German)

In den modernen Industrienationen haben sich chronische nichtübertragbare Krankheiten zur Hauptursache menschlicher Sterblichkeit entwickelt. Während der letzten Jahre wuchs die globale Belastung der Gesundheitssysteme durch chronische Nierenleiden beträchtlich und in vielen dieser Fälle sind weder gezielte noch personalisierte Therapien verfügbar. Um mit den steigenden Herausforderungen ...


Export bibliographical data

Item type:Thesis of the University of Regensburg (PhD)
Date:22 August 2019
Referee:Prof. Dr. Dr. Michael Krahn
Date of exam:9 October 2018
Institutions:Biology, Preclinical Medicine > Institut für Anatomie > Lehrstuhl für Molekulare und zelluläre Anatomie
Keywords:nephrocyte; slit diaphragm; endocytosis; cell polarity; cell signaling; high pressure freezing; tomography; transmission electron microscopy; STEM; Crumbs; Moesin; podocyte; Mpp5; Pals1; cystic kidney; proteinuria
Dewey Decimal Classification:500 Science > 570 Life sciences
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:40676
Owner only: item control page


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