Cyclosporine A Impairs Norepinephrine-Induced Vascular Contractility

URN to cite this document:: urn:nbn:de:bvb:355-epub-408883
DOI to cite this document:: 10.5283/epub.40888

Bergler, Tobias ; Resch, Markus ; Reinhold, Stephan W. ; Birner, Christoph ; Jungbauer, Carsten G. ; Griese, Daniel P. ; Schmid, Peter ; Banas, Bernhard

; Endemann, Dierk

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Date of publication of this fulltext: 23 Oct 2019 08:52

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Abstract

Usage of cyclosporine A (CsA) after kidney transplantation may be associated with development of nephrotoxicity and vasculopathy, but the mechanisms by which CsA causes vascular dysfunction are still under scrutiny. We established a transplantation model and investigated the effect of CsA on vascular contractility with the aid of a pressurized myograph in comparison with control and unilaterally ...