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Cyclosporine A Impairs Norepinephrine-Induced Vascular Contractility

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Bergler, Tobias ; Resch, Markus ; Reinhold, Stephan W. ; Birner, Christoph ; Jungbauer, Carsten G. ; Griese, Daniel P. ; Schmid, Peter ; Banas, Bernhard ; Endemann, Dierk
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Date of publication of this fulltext: 23 Oct 2019 08:52


Usage of cyclosporine A (CsA) after kidney transplantation may be associated with development of nephrotoxicity and vasculopathy, but the mechanisms by which CsA causes vascular dysfunction are still under scrutiny. We established a transplantation model and investigated the effect of CsA on vascular contractility with the aid of a pressurized myograph in comparison with control and unilaterally ...


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