Go to content
UR Home

Downregulation of the Ubiquitin-Proteasome System in Normal Colonic Macrophages and Reinduction in Inflammatory Bowel Disease

Hetzenegger, A.M., Seidl, M.C., Kosovac, K., Herfarth, H., Kellermeier, S., Obermeier, Florian, Falk, Werner, Schölmerich, Jürgen and Rogler, Gerhard (2012) Downregulation of the Ubiquitin-Proteasome System in Normal Colonic Macrophages and Reinduction in Inflammatory Bowel Disease. Digestion 86, pp. 34-47.

[img]
Preview
PDF - Published Version
Download (1MB)
Date of publication of this fulltext: 23 Oct 2019 10:01

at publisher (via DOI)

Other URL: https://www.karger.com/Article/FullText/336353


Abstract

Background: In normal mucosa, intestinal lamina propria macrophages (IMACs) maintain tolerance against food antigens and the commensal bacterial flora. Several mechanisms have been identified that mediate tolerance. The ubiquitin-proteasome system (UPS) is a large multiprotein complex that degrades cellular proteins. As the UPS may modulate immune functions of IMACs, we performed a detailed ...

plus


Export bibliographical data



Item type:Article
Date:2012
Additional Information (public):OA-Komponente aus Allianzlizenz
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Identification Number:
ValueType
10.1159/000336353DOI
Keywords:Intestinal macrophages, Proteasome, Immunoproteasome, Ubiquitin, Tolerance
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:40892
Owner only: item control page

Downloads

Downloads per month over past year

  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons