Obesity and Fatty Liver Are 'Grease' for the Machinery of Hepatic Fibrosis

URN to cite this document:: urn:nbn:de:bvb:355-epub-409072
DOI to cite this document:: 10.5283/epub.40907

Bosserhoff, Anja K. ; Hellerbrand, Claus

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Date of publication of this fulltext: 24 Oct 2019 13:31

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Abstract

Nonalcoholic fatty liver disease (NAFLD) starts with hepatic steatosis, which can progress with inflammation to nonalcoholic steatohepatitis, and a subset of patients develop progressive fibrosis and ultimately cirrhosis. In the majority of cases, NAFLD is associated with (components of) the metabolic syndrome. Obesity, diabetes and hepatic steatosis are also independent risk factors for hepatic ...