Role of the Hepatic Parenchyma in Liver Transplant Tolerance: A Paradigm Revisited

URN to cite this document:: urn:nbn:de:bvb:355-epub-409080
DOI to cite this document:: 10.5283/epub.40908

Benseler, Volker ; Tay, S. S. ; Bowen, D. G. ; Bertolino, P.

Preview

PDF - Published Version
(232kB)

Date of publication of this fulltext: 24 Oct 2019 13:38

Alternative links to fulltext:DOI Publisher

Details

Preview

Export bibliographical data

Abstract

Unlike other solid organs, liver transplants are spontaneously accepted in a wide range of animal models. In the clinic, transplanted livers also display privileged immunological properties allowing weaning of immunosuppression therapy in up to 20% of selected patients. To explain this phenomenon, many studies have focused on the role of donor-derived ‘passenger’ leukocytes that are thought to ...