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Traditional and Nontraditional Cardiovascular Risk Factors and Estimated Risk for Coronary Artery Disease in Renal Transplant Recipients: A Single-Center Experience
Banas, Miriam C., Banas, Bernhard
, Orth, Stephan R., Langer, Veronika, Reinhold, Stephan W., Weingart, Christian, Jung, Bettina, Krüger, Bernd und Krämer, Bernhard K.
(2011)
Traditional and Nontraditional Cardiovascular Risk Factors and Estimated Risk for Coronary Artery Disease in Renal Transplant Recipients: A Single-Center Experience.
Nephron Clinical Practice 119, c227-c235.
Veröffentlichungsdatum dieses Volltextes: 24 Okt 2019 13:59
Artikel
DOI zum Zitieren dieses Dokuments: 10.5283/epub.40910
Zusammenfassung
Background/Aims: The prevalence of cardiovascular disease in renal transplant recipients is markedly higher than in the general population due to the high prevalence of traditional cardiovascular risk factors, renal transplant function impairment and treatment with immunosuppressive drugs that affect blood pressure, cholesterol and blood glucose levels. Methods: Cross-sectional analysis using our ...
Background/Aims: The prevalence of cardiovascular disease in renal transplant recipients is markedly higher than in the general population due to the high prevalence of traditional cardiovascular risk factors, renal transplant function impairment and treatment with immunosuppressive drugs that affect blood pressure, cholesterol and blood glucose levels. Methods: Cross-sectional analysis using our renal transplant clinic cohort investigating (1) the cardiovascular risk factors present in this cohort, and (2) estimating their impact on the risk of coronary artery disease (CAD) by using the Framingham algorithm. Results: Control of modifiable cardiovascular risk factors in 231 renal transplant recipients is suboptimal, i.e. 47.2% of patients are hypertensive, 10.3% actively smoke, 39.4% have serum cholesterol concentrations >200 mg/dl, and 19.7% have diabetes mellitus. Blood pressure, age, hyperlipidemia, smoking and diabetes modulate the estimated CAD risk in males and females. Furthermore, a short time period (less than 1 year) since transplantation and increased serum creatinine levels negatively influenced the CAD risk in this patient population. Conclusion: According to current guidelines, the control of modifiable cardiovascular risk factors in renal transplant recipients is suboptimal. The decreasing CAD risk over time after transplantation may be due to the reduction of immunosuppressive drugs with time and survival bias. Copyright (C) 2011 S. Karger AG, Basel-
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| Dokumentenart | Artikel | ||||
| Titel eines Journals oder einer Zeitschrift | Nephron Clinical Practice | ||||
| Verlag: | KARGER | ||||
|---|---|---|---|---|---|
| Ort der Veröffentlichung: | BASEL | ||||
| Band: | 119 | ||||
| Seitenbereich: | c227-c235 | ||||
| Datum | 2011 | ||||
| Zusätzliche Informationen (Öffentlich) | OA-Komponente aus Allianzlizenz | ||||
| Institutionen | Medizin > Lehrstuhl für Innere Medizin II | ||||
| Identifikationsnummer |
| ||||
| Stichwörter / Keywords | HEART-DISEASE; BLOOD-PRESSURE; FAILURE; SMOKING; Hypertension; Smoking; Hyperlipidemia; Diabetes; Risk factor control; Immunosuppression; Kidney transplantation; Statins | ||||
| Dewey-Dezimal-Klassifikation | 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin | ||||
| Status | Veröffentlicht | ||||
| Begutachtet | Ja, diese Version wurde begutachtet | ||||
| An der Universität Regensburg entstanden | Ja | ||||
| URN der UB Regensburg | urn:nbn:de:bvb:355-epub-409104 | ||||
| Dokumenten-ID | 40910 |
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