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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-409954
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.40995
Zusammenfassung
The tumor suppressor gene p53 plays an important role in the stress response of the cell and is mutated in 50% of all human tumors. The p53 Arg72Pro single-nucleotide polymorphism (SNP) was found to be associated with an increased risk of various malignancies. Biochemical and biological differences between the 2 polymorphic variants of wild-type P53 might lead to distinct susceptibility to HPV- ...
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