Go to content
UR Home

11-β hydroxysteroid type 1 knockout mice display an antidepressant-like phenotype in the forced swim test

URN to cite this document:
DOI to cite this document:
Slattery, David A. ; Uzunov, Doncho P. ; Cryan, John F.
PDF - Published Version
Date of publication of this fulltext: 20 Nov 2019 13:55


Objective 11-dehydroxysteroid dehydrogenase (HSD) types 1 and 2, enzymes are involved in the activation and inactivation of glucocorticoids in vivo, respectively. Indirect evidence implicates two enzymes in the aetiology of depression but no study has directly assessed the potential role of 11 -HSD1 in animal tests. Methods We assessed 11 -HSD1 knockout mice in the forced swim test (FST), tail ...


Owner only: item control page
  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons