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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-410580
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.41058
Zusammenfassung
Objective 11-dehydroxysteroid dehydrogenase (HSD) types 1 and 2, enzymes are involved in the activation and inactivation of glucocorticoids in vivo, respectively. Indirect evidence implicates two enzymes in the aetiology of depression but no study has directly assessed the potential role of 11 -HSD1 in animal tests. Methods We assessed 11 -HSD1 knockout mice in the forced swim test (FST), tail ...
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