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Gray matter alterations in visual cortex of patients with loss of central vision due to hereditary retinal dystrophies

Plank, Tina ; Frolo, Jozef ; Brandl-Rühle, Sabine ; Renner, Agnes B. ; Hufendiek, Karsten ; Helbig, Horst ; Greenlee, Mark W.



Abstract

In patients with central visual field scotomata a large part of visual cortex is not adequately stimulated. Over time this lack of input could lead to a reduction of gray matter in the affected cortical areas. We used Voxel Based Morphometry to investigate structural brain changes in patients with central scotomata due to hereditary retinal dystrophies and compared their results to those of ...

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