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Impaired working-memory after cerebellar infarcts paralleled by changes in BOLD signal of a cortico-cerebellar circuit

Ziemus, B. ; Baumann, Oliver ; Luerding, Ralf ; Schlosser, R. ; Schuierer, Gerhard ; Bogdahn, Ulrich ; Greenlee, Mark W.


A considerable body of evidence supports the notion that cerebellar lesions lead to neuropsychological deficits, including impairments in working-memory, executive tasks and verbal fluency. Studies employing functional magnetic resonance imaging (fMRI) and anatomical tracing in primates provide evidence for a cortico-cerebellar circuitry as the functional substrate of working-memory. The present ...


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