Comprehensive Assessment of GPR68 Expression in Normal and Neoplastic Human Tissues Using a Novel Rabbit Monoclonal Antibody

URN to cite this document:: urn:nbn:de:bvb:355-epub-415221
DOI to cite this document:: 10.5283/epub.41522

Herzig, M. ; Dasgupta, P. ; Kaemmerer, D. ; Evert, Katja

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Date of publication of this fulltext: 07 Feb 2020 10:39

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Abstract

GPR68 (OGR1) belongs to the proton-sensing G protein-coupled receptors that are involved in cellular adaptations to pH changes during tumour development. Although expression of GPR68 has been described in many tumour cell lines, little is known about its presence in human tumour entities. We characterised the novel rabbit monoclonal anti-human GPR68 antibody 16H23L16 using various cell lines and ...