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The Effect of Dexamethasone, Adrenergic and Cholinergic Receptor Agonists on Phospholipid Metabolism in Human Osteoarthritic Synoviocytes

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Sluzalska, Katarzyna D. ; Liebisch, Gerhard ; Ishaque, Bernd ; Schmitz, Gerd
License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 10 Feb 2020 09:44


Phospholipids (PLs) possess the unique ability to contribute to synovial joint lubrication. The aim of our study was to determine for the first time the effect of dexamethasone and some adrenergic and cholinergic agonists on the biosynthesis and release of PLs from human fibroblast-like synoviocytes (FLS). Osteoarthritic human knee FLS were treated with dexamethasone, terbutaline, epinephrine, ...


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