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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-415787
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.41578
Zusammenfassung
Ca2+ activated Cl- channels (TMEM16A; ANO1) support cell proliferation and cancer growth. Expression of TMEM16A is strongly enhanced in different types of malignomas. In contrast, TMEM16F (ANO6) operates as a Ca2+ activated chloride/nonselective ion channel and scrambles membrane phospholipids to expose phosphatidylserine at the cell surface. Both phospholipid scrambling and cell swelling induced ...
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