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Expression of the Receptor for Advanced Glycation End Products in Epicardial Fat: Link with Tissue Thickness and Local Insulin Resistance in Coronary Artery Disease

Dozio, Elena ; Vianello, Elena ; Briganti, Silvia ; Lamont, John ; Tacchini, Lorenza ; Schmitz, Gerd ; Corsi Romanelli, Massimiliano Marco



Abstract

Increased expression of receptor for advanced glycation end products (RAGE) in adipose tissue has been associated with inflammation, adipocyte hypertrophy, and impaired insulin signal. Epicardial adipose tissue (EAT), a visceral fat surrounding the myocardium, is potentially involved in the onset/progression of coronary artery disease (CAD). To date, the role of RAGE in EAT has not been explored ...

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