Pregler, B. ; Beyer, L. P. 
; Wiesinger, I. ; Nießen, C. ; Jung, E. M. ; Stroszczynski, C. ; Wiggermann, P. ; Jung, F. ; Gori, T.
Alternative Links zum Volltext:DOIVerlag
| Dokumentenart: | Artikel |
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| Titel eines Journals oder einer Zeitschrift: | Clinical Hemorheology and Microcirculation |
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| Verlag: | IOS PRESS |
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| Ort der Veröffentlichung: | AMSTERDAM |
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| Band: | 64 |
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| Nummer des Zeitschriftenheftes oder des Kapitels: | 3 |
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| Seitenbereich: | S. 483-490 |
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| Datum: | 2017 |
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| Institutionen: | Medizin > Lehrstuhl für Röntgendiagnostik |
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| Identifikationsnummer: | | Wert | Typ |
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| 10.3233/CH-168113 | DOI |
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| Stichwörter / Keywords: | HEPATOCELLULAR-CARCINOMA; RADIOFREQUENCY ABLATION; CIRRHOSIS; SPECTRUM; LIVER; Contrast-enhanced ultrasound (CEUS); microwave ablation (MWA); hepatocellular carcinoma (HCC); imaging findings |
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| Dewey-Dezimal-Klassifikation: | 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin |
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| Status: | Veröffentlicht |
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| Begutachtet: | Ja, diese Version wurde begutachtet |
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| An der Universität Regensburg entstanden: | Ja |
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| Dokumenten-ID: | 41817 |
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Web of Science
Zusammenfassung
PURPOSE: To assess the value of dynamic contrast enhanced ultrasound (CEUS) for the detection of residual tumor tissue day 1 after microwave ablation (MWA) of large hepatocellular carcinoma (HCC) compared to MRI. MATERIAL AND METHODS: 30 consecutive patients (5 females, 25 males, mean age 64 years, age range 54-73 years) with an untreated HCC lesion larger than or equal to 3 cm underwent ...
Zusammenfassung
PURPOSE: To assess the value of dynamic contrast enhanced ultrasound (CEUS) for the detection of residual tumor tissue day 1 after microwave ablation (MWA) of large hepatocellular carcinoma (HCC) compared to MRI. MATERIAL AND METHODS: 30 consecutive patients (5 females, 25 males, mean age 64 years, age range 54-73 years) with an untreated HCC lesion larger than or equal to 3 cm underwent percutaneous MWA between 03/2014 and 04/2016. 1 patient was excluded because of an artificial pacemaker. All remaining 29 patients underwent 3-T MRI with liver-specific contrast agent and CEUS 1 day after ablation to detect residual tumor tissue. The 6-week follow-up including CEUS and MRI was defined as the reference standard. RESULTS: Complete ablation was achieved in 23 of 29 treated lesions (79%). The sensitivities and specificities for the detection of residual tumor tissue on day 1 were 100% and 83% for CEUS and 87% and 67% for MRI resp. without the differences being statistically significant. CONCLUSION: CEUS allows a reliable assessment of therapeutic success of percutaneous ablation of large HCC lesions one day after the ablation. Its ability to visualize reactive periablation perfusion changes in real-time might be of advantage in the depiction of residual tumor tissue when compared to MRI imaging alone.
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