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Bile Acid Metabolome after an Oral Lipid Tolerance Test by Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Huang, Wendong ; Schmid, Andreas ; Neumann, Hannah ; Karrasch, Thomas ; Liebisch, Gerhard ; Schäffler, Andreas



Abstract

Context Besides their role in intestinal resorption of lipids, bile acids are regarded as endocrine and metabolic signaling molecules. The detailed profile of bile acid species in peripheral blood after an oral lipid tolerance test (OLTT) is unknown. Objective We quantified the regulation of 18 bile acids after OLTT in healthy individuals. Material and methods 100 volunteers were characterized by ...

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