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Norepinephrine modulates osteoarthritic chondrocyte metabolism and inflammatory responses

Lorenz, J. ; Schäfer, N. ; Bauer, R. ; Jenei-Lanzl, Z. ; Springorum, R. H. ; Grässel, S.



Zusammenfassung

Objective: Norepinephrine (NE) was measured in synovial fluid of trauma patients and sympathetic nerve fibers were detected in healthy and osteoarthritic (OA) joint tissues indicating that cartilage pathophysiology might be influenced by sympathetic neurotransmitters. The aim of this study was to elucidate the mostly unknown role of NE in OA chondrocyte metabolism and inflammatory responses. ...

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