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Prefabrication and free transfer of a tissue engineered composite flap – An experimental model in the rat

Mandlik, V. ; Kehrer, A. ; Jiga, L. ; Hoinoiu, B. ; Ionac, M. ; Jung, F. ; Staudenmaier, R. ; Prantl, L. ; Jung, F. ; Gori, T.


BACKGROUND: The technique of flap-prefabrication has been successfully established in tissue engineering: missing intrinsic vascularisation of engineered tissue can be generated in vivo by microsurgical vesselloop construction. It is possible to move engineered tissue into a defect with microsurgery. In the literature, the combination of engineered tissue covered with skin is not widely reported. ...


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