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Investigating non-specific binding to chemically engineered sensor surfaces using liposomes as models

Fenzl, C. ; Genslein, C. ; Domonkos, C. ; Edwards, K. A. ; Hirsch, T. ; Baeumner, A. J.



Abstract

Nanoparticles are ubiquitously used for signal enhancement in (bio)sensors, but their true possible performance is typically hampered by non-specific binding. A better understanding of the nature and the prevention of non-specific binding through surface engineering of the particles and sensor surfaces is needed to intelligently design (bio) sensors and potentially avoid bulk blocking methods. ...

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