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Improved Detection of preclinical Colorectal Liver Metastases by High Resolution Ultrasound including Molecular Ultrasound Imaging using the targeted Contrast Agent BR55

Hackl, C. ; Schacherer, D. ; Anders, M. ; Wiedemann, L. ; Mohr, A. ; Schlitt, H. ; Stroszczynski, C. ; Tranquart, F. ; Jung, E.


Purpose: Aim of the present study was to investigate the sensitivity of high resolution ultrasound (HRU), standard contrast-enhanced ultrasound (CEUS) and CEUS using a novel vascular endothelial growth factor receptor 2 (VEGFR2)-targeted contrast agent for the detection of hepatic metastases in a mouse model of colorectal cancer using clinical standard technology. Materials and Methods: The human ...


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