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Eisosomes promote the ability of Sur7 to regulate plasma membrane organization in Candida albicans

Wang, Hong X. ; Douglas, Lois M. ; Veselá, Petra ; Rachel, Reinhard ; Malinsky, Jan ; Konopka, James B. ; Lew, Daniel J.



Abstract

The plasma membrane of the fungal pathogen Candida albicans forms a protective barrier that also mediates many processes needed for virulence, including cell wall synthesis, invasive hyphal morphogenesis, and nutrient uptake. Because compartmentalization of the plasma membrane is believed to coordinate these diverse activities, we examined plasma membrane microdomains termed eisosomes or membrane ...

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