Ehrenstein, B. ; Reischl, U.
Alternative Links zum Volltext:DOIVerlag
Dokumentenart: | Artikel |
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Titel eines Journals oder einer Zeitschrift: | Zeitschrift für Rheumatologie |
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Verlag: | SPRINGER HEIDELBERG |
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Ort der Veröffentlichung: | HEIDELBERG |
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Band: | 75 |
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Nummer des Zeitschriftenheftes oder des Kapitels: | 4 |
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Seitenbereich: | S. 381-388 |
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Datum: | 2016 |
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Institutionen: | Medizin > Lehrstuhl für Orthopädie |
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Identifikationsnummer: | Wert | Typ |
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10.1007/s00393-016-0058-6 | DOI |
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Stichwörter / Keywords: | POLYMERASE-CHAIN-REACTION; WHIPPLES-DISEASE; REACTIVE ARTHRITIS; PNEUMOCYSTIS PNEUMONIA; DOUBLE-BLIND; DIAGNOSIS; IDENTIFICATION; DNA; CHLAMYDIA; INFECTION; Borreliosis; Lyme arthritis; Reactive arthritis; Infection; Immunosuppression |
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Dewey-Dezimal-Klassifikation: | 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin |
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Status: | Veröffentlicht |
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Begutachtet: | Ja, diese Version wurde begutachtet |
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An der Universität Regensburg entstanden: | Ja |
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Dokumenten-ID: | 42230 |
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Web of Science
Zusammenfassung
In the differential diagnostics of autoimmune-mediated rheumatic diseases, rheumatologists often have to consider infections (e. g. Lyme arthritis) or reactive diseases (e. g. reactive arthritis after urogenital bacterial infections). Furthermore, infections with an atypical presentation or caused by atypical pathogens (opportunistic infections) can complicate the immunosuppressive therapy of ...
Zusammenfassung
In the differential diagnostics of autoimmune-mediated rheumatic diseases, rheumatologists often have to consider infections (e. g. Lyme arthritis) or reactive diseases (e. g. reactive arthritis after urogenital bacterial infections). Furthermore, infections with an atypical presentation or caused by atypical pathogens (opportunistic infections) can complicate the immunosuppressive therapy of autoimmune diseases. For this purpose not only conventional microbiological culture methods but also PCR-based methods are increasingly being applied for the direct detection of pathogens in clinical specimens. The aim of this overview is to present commonly used PCR methods in the clinical practice of rheumatology and to describe their benefits and limitations compared to culture-based detection methods.