Abstract
Visible-light photoredox catalysis has emerged as a powerful tool for organic synthesis, but cost-effective, scalable processes are still underdeveloped. In this issue of Chem, Stephenson and coworkers demonstrate such technology in combination with continuous flow for trifluoromethylations of heteroarenes on a kilogram scale by utilizing readily available trifluoroacetic anhydride as a ...
Abstract
Visible-light photoredox catalysis has emerged as a powerful tool for organic synthesis, but cost-effective, scalable processes are still underdeveloped. In this issue of Chem, Stephenson and coworkers demonstrate such technology in combination with continuous flow for trifluoromethylations of heteroarenes on a kilogram scale by utilizing readily available trifluoroacetic anhydride as a trifluoromethyl source. The resulting compounds and the underlying methodology are of great relevance in medicinal chemistry.
Altmetric