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Milk miRNAs: simple nutrients or systemic functional regulators?

Melnik, Bodo C. ; Kakulas, Foteini ; Geddes, Donna T. ; Hartmann, Peter E. ; John, Swen Malte ; Carrera-Bastos, Pedro ; Cordain, Loren ; Schmitz, Gerd



Abstract

Milk is rich in miRNAs that appear to play important roles in the postnatal development of all mammals. Currently, two competing hypotheses exist: the functional hypothesis, which proposes that milk miRNAs are transferred to the offspring and exert physiological regulatory functions, and the nutritional hypothesis, which suggests that these molecules do not reach the systemic circulation of the ...

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