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Comparative analysis of the effect of prostatic invasion patterns on cancer-specific mortality after radical cystectomy in pT4a urothelial carcinoma of the bladder

Vallo, Stefan ; Gilfrich, Christian ; Burger, Maximilian ; Volkmer, Björn ; Boehm, Katharina ; Rink, Michael ; Chun, Felix K. ; Roghmann, Florian ; Novotny, Vladimir ; Mani, Jens ; Brisuda, Antonin ; Mayr, Roman ; Stredele, Regina ; Noldus, Joachim ; Schnabel, Marco ; May, Matthias ; Fritsche, Hans-Martin ; Pycha, Armin ; Martini, Thomas ; Wirth, Manfred ; Roigas, Jan ; Bastian, Patrick J. ; Nuhn, Philipp ; Dahlem, Roland ; Haferkamp, Axel ; Fisch, Margit ; Aziz, Atiqullah



Abstract

Purpose: To evaluate the prognostic relevance of different prostatic invasion patterns in pT4a urothelial carcinoma of the bladder (UCB) after radical cystectomy. Materials and methods: Our study comprised a total of 358 men with pT4a UCB. Patients were divided in 2 groups-group A with stromal infiltration of the prostate via the prostatic urethra with additional muscle-invasive UCB (n = 121, ...

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