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Autoimmune diseases and immunosuppressive therapy in relation to the risk of glioma

Anssar, Tareq M. ; Leitzmann, Michael F. ; Linker, Ralf A. ; Meier, Christoph ; Becker, Claudia ; Jick, Susan ; Sahm, Katharina ; Platten, Michael ; Hau, Peter ; Seliger, Corinna
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Date of publication of this fulltext: 09 Apr 2020 16:47


Abstract

Effectors from the immune system can modulate the course and possibly the early development of gliomas. We, therefore, hypothesized that autoimmune diseases associated with increased immune‐surveillance may also modulate the risk of human glioma. To test this hypothesis, we used data from the well‐validated Clinical Practice Research Datalink (CPRD) GOLD from the UK to analyze the association of ...

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