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Myocyte Enhancer Factor 2A (MEF2A) Defines Oxytocin-Induced Morphological Effects and Regulates Mitochondrial Function in Neurons

Meyer, Magdalena ; Kuffner, Kerstin ; Winter, Julia ; Neumann, Inga D. ; Wetzel, Christian H. ; Jurek, Benjamin
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Date of publication of this fulltext: 15 Apr 2020 12:51


Abstract

The neuropeptide oxytocin (OT) is a well-described modulator of socio-emotional traits, such as anxiety, stress, social behavior, and pair bonding. However, when dysregulated, it is associated with adverse psychiatric traits, such as various aspects of autism spectrum disorder (ASD). In this study, we identify the transcription factor myocyte enhancer factor 2A (MEF2A) as the common link between ...

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