Go to content
UR Home

Acquired resistance to DZNep-mediated apoptosis is associated with copy number gains of AHCY in a B-cell lymphoma model

URN to cite this document:
DOI to cite this document:
Akpa, C. A. ; Kleo, K. ; Oker, E. ; Tomaszewski, N. ; Messerschmidt, C. ; López, C. ; Wagener, R. ; Oehl-Huber, K. ; Dettmer, Katja ; Schoeler, A. ; Lenze, D. ; Oefner, Peter J. ; Beule, D. ; Siebert, R. ; Capper, D. ; Dimitrova, L. ; Hummel, M.
License: Creative Commons Attribution 4.0
PDF - Published Version
Date of publication of this fulltext: 18 May 2020 14:09


BackgroundEnhancer of zeste homolog 2 (EZH2) is considered an important driver of tumor development and progression by its histone modifying capabilities. Inhibition of EZH2 activity is thought to be a potent treatment option for eligible cancer patients with an aberrant EZH2 expression profile, thus the indirect EZH2 inhibitor 3-Deazaneplanocin A (DZNep) is currently under evaluation for its ...


Owner only: item control page
  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons