Ca2+ release and buffering effects of synthetic hydroxyapatite following bacterial acid challenge

URN to cite this document:: urn:nbn:de:bvb:355-epub-442220
DOI to cite this document:: 10.5283/epub.44222

Cieplik, Fabian

; Rupp, Christina M. ; Hirsch, Stefanie ; Muehler, Denise ; Enax, Joachim ; Meyer, Frederic ; Hiller, Karl-Anton ; Buchalla, Wolfgang

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Date of publication of this fulltext: 22 Jan 2021 15:23

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Abstract

Background Synthetic particulate hydroxyapatite (HAP; Ca-5(PO4)(3)(OH)) is used as ingredient in oral care products but its effects on cariogenic biofilms are not clear yet. The primary mode of action of HAP may be acting as a calcium phosphate reservoir when deposited in oral biofilms and release Ca2+ and (hydrogen) phosphate ions upon bacterial acid challenge. The aim of this in vitro study was ...