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Ca2+ release and buffering effects of synthetic hydroxyapatite following bacterial acid challenge

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Cieplik, Fabian ; Rupp, Christina M. ; Hirsch, Stefanie ; Muehler, Denise ; Enax, Joachim ; Meyer, Frederic ; Hiller, Karl-Anton ; Buchalla, Wolfgang
License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 22 Jan 2021 15:23


Background Synthetic particulate hydroxyapatite (HAP; Ca-5(PO4)(3)(OH)) is used as ingredient in oral care products but its effects on cariogenic biofilms are not clear yet. The primary mode of action of HAP may be acting as a calcium phosphate reservoir when deposited in oral biofilms and release Ca2+ and (hydrogen) phosphate ions upon bacterial acid challenge. The aim of this in vitro study was ...


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