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- URN to cite this document:
- urn:nbn:de:bvb:355-epub-442745
- DOI to cite this document:
- 10.5283/epub.44274
Abstract
Aims Recent clinical trials have proven gliflozins to be cardioprotective in diabetic and non-diabetic patients. However, the underlying mechanisms are incompletely understood. A potential inhibition of cardiac Na+/H(+)exchanger 1 (NHE1) has been suggested in animal models. We investigated the effect of empagliflozin on NHE1 activity in human atrial cardiomyocytes. Methods and results Expression ...

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