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Decreased GLUT1/NHE1 RNA expression in whole blood predicts disease severity in patients with COVID‐19

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Mustroph, Julian ; Hupf, Julian ; Hanses, Frank ; Evert, Katja ; Baier, Maria J. ; Evert, Matthias ; Meindl, Christine ; Wagner, Stefan ; Hubauer, Ute ; Pietrzyk, Gabriela ; Leininger, Simon ; Staudner, Stephan ; Vogel, Manuel ; Wallner, Stefan ; Zimmermann, Markus ; Sossalla, Samuel ; Maier, Lars S. ; Jungbauer, Carsten
License: Creative Commons Attribution Non-commercial 4.0
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Date of publication of this fulltext: 14 Jan 2021 16:23


Aims We aimed to assess whether expression of whole‐blood RNA of sodium proton exchanger 1 (NHE1) and glucose transporter 1 (GLUT1) is associated with COVID‐19 infection and outcome in patients presenting to the emergency department with respiratory infections. Furthermore, we investigated NHE1 and GLUT1 expression in the myocardium of deceased COVID‐19 patients. Methods and ...


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