Decreased GLUT1/NHE1 RNA expression in whole blood predicts disease severity in patients with COVID‐19

URN to cite this document:: urn:nbn:de:bvb:355-epub-442751
DOI to cite this document:: 10.5283/epub.44275

Mustroph, Julian ; Hupf, Julian ; Hanses, Frank ; Evert, Katja ; Baier, Maria J. ; Evert, Matthias ; Meindl, Christine ; Wagner, Stefan

; Hubauer, Ute ; Pietrzyk, Gabriela ; Leininger, Simon ; Staudner, Stephan ; Vogel, Manuel ; Wallner, Stefan ; Zimmermann, Markus ; Sossalla, Samuel ; Maier, Lars S. ; Jungbauer, Carsten

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Date of publication of this fulltext: 14 Jan 2021 16:23

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Abstract

Aims We aimed to assess whether expression of whole‐blood RNA of sodium proton exchanger 1 (NHE1) and glucose transporter 1 (GLUT1) is associated with COVID‐19 infection and outcome in patients presenting to the emergency department with respiratory infections. Furthermore, we investigated NHE1 and GLUT1 expression in the myocardium of deceased COVID‐19 patients. Methods and ...