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Decreased GLUT1/NHE1 RNA expression in whole blood predicts disease severity in patients with COVID‐19

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Mustroph, Julian ; Hupf, Julian ; Hanses, Frank ; Evert, Katja ; Baier, Maria J. ; Evert, Matthias ; Meindl, Christine ; Wagner, Stefan ; Hubauer, Ute ; Pietrzyk, Gabriela ; Leininger, Simon ; Staudner, Stephan ; Vogel, Manuel ; Wallner, Stefan ; Zimmermann, Markus ; Sossalla, Samuel ; Maier, Lars S. ; Jungbauer, Carsten
License: Creative Commons Attribution Non-commercial 4.0
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Date of publication of this fulltext: 14 Jan 2021 16:23


Aims We aimed to assess whether expression of whole-blood RNA of sodium proton exchanger 1 (NHE1) and glucose transporter 1 (GLUT1) is associated with COVID-19 infection and outcome in patients presenting to the emergency department with respiratory infections. Furthermore, we investigated NHE1 and GLUT1 expression in the myocardium of deceased COVID-19 patients. Methods and results Whole-blood ...


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