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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-443037
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.44303
Zusammenfassung
Stabilization of the HIV-1 Envelope glycoprotein trimer (Env) in its native pre-fusion closed conformation is regarded as one of several requirements for the induction of neutralizing antibody (nAb) responses, which, in turn, will most likely be a prerequisite for the development of an efficacious preventive vaccine. Here, we systematically analyzed how the stepwise stabilization of a clade C ...
