Go to content
UR Home

Fasudil Loaded PLGA Microspheres as Potential Intravitreal Depot Formulation for Glaucoma Therapy

URN to cite this document:
DOI to cite this document:
Mietzner, Raphael ; Kade, Christian ; Froemel, Franziska ; Pauly, Diana ; Stamer, W. Daniel ; Ohlmann, Andreas ; Wegener, Joachim ; Fuchshofer, Rudolf ; Breunig, Miriam
License: Creative Commons Attribution 4.0
PDF - Published Version
Date of publication of this fulltext: 15 Jan 2021 10:41


Rho-associated protein kinase (ROCK) inhibitors allow for causative glaucoma therapy. Unfortunately, topically applied ROCK inhibitors suffer from high incidence of hyperemia and low intraocular bioavailability. Therefore, we propose the use of poly (lactide-co-glycolide) (PLGA) microspheres as a depot formulation for intravitreal injection to supply outflow tissues with the ROCK inhibitor ...


Owner only: item control page
  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons