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Angiotensin-converting enzyme inhibitor/angiotensin II receptor blocker treatment and haemodynamic factors are associated with increased cardiac mRNA expression of angiotensin-converting enzyme 2 in patients with cardiovascular disease

URN to cite this document:
urn:nbn:de:bvb:355-epub-445057
DOI to cite this document:
10.5283/epub.44505
Lebek, Simon ; Tafelmeier, Maria ; Messmann, Rebecca ; Provaznik, Zdenek ; Schmid, Christof ; Maier, Lars S. ; Birner, Christoph ; Arzt, Michael ; Wagner, Stefan
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Date of publication of this fulltext: 26 Jan 2021 16:19


Abstract

Aims Coronavirus disease 2019 (COVID-19) is a widespread pandemic with an increased morbidity and mortality, especially for patients with cardiovascular diseases. Angiotensin-converting enzyme 2 (ACE2) has been identified as necessary cell entry point for SARS-CoV-2. Previous animal studies have demonstrated an increased ACE2 expression following treatment with either angiotensin-converting ...

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