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Cationic liposomes for generic signal amplification strategies in bioassays

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Baeumner, Antje J. ; Hofmann, Carola ; Kaiser, Barbara ; Maerkl, Susanne ; Duerkop, Axel
License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 28 Jan 2021 09:24

This publication is part of the DEAL contract with Springer.


Liposomes have been widely applied in bioanalytical assays. Most liposomes used bare negative charges to prevent non-specific binding and increase colloidal stability. Here, in contrast, highly stable, positively charged liposomes entrapping the fluorescent dye sulforhodamine B (SRB) were developed to serve as a secondary, non-specific label, and signal amplification tool in bioanalytical systems ...


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