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A highly specific and sensitive serological assay detects SARS‑CoV‑2 antibody levels in COVID‑19 patients that correlate with neutralization

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Peterhoff, David ; Glück, Vivian ; Vogel, Matthias ; Schuster, Philipp ; Schütz, Anja ; Neubert, Philip ; Albert, Veruschka ; Frisch, Stefanie ; Kiessling, Mara ; Pervan, Philip ; Werner, Maren ; Ritter, Nicole ; Babl, Leon ; Deichner, Maria ; Hanses, Frank ; Lubnow, Matthias ; Müller, Thomas ; Lunz, Dirk ; Hitzenbichler, Florian ; Audebert, Franz ; Hähnel, Viola ; Offner, Robert ; Müller, Martina ; Schmid, Stephan ; Burkhardt, Ralph ; Glück, Thomas ; Koller, Michael ; Niller, Hans Helmut ; Graf, Bernhard ; Salzberger, Bernd ; Wenzel, Jürgen J. ; Jantsch, Jonathan ; Gessner, André ; Schmidt, Barbara ; Wagner, Ralf
License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 02 Feb 2021 14:10

This publication is part of the DEAL contract with Springer.


Objective The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic challenges national health systems and the global economy. Monitoring of infection rates and seroprevalence can guide public health measures to combat the pandemic. This depends on reliable tests on active and former infections. Here, we set out to develop and validate a specific and sensitive enzyme linked ...


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