Go to content
UR Home

Inhibition of NaV1.8 prevents atrial arrhythmogenesis in human and mice

URN to cite this document:
urn:nbn:de:bvb:355-epub-448037
DOI to cite this document:
10.5283/epub.44803
Pabel, Steffen ; Ahmad, Shakil ; Tirilomis, Petros ; Stehle, Thea ; Mustroph, Julian ; Holzamer, Andreas ; Hilker, Michael ; Maier, Lars S. ; Sossalla, Samuel ; ; ; ; ;
[img]
Preview
License: Creative Commons Attribution 4.0
PDF - Published Version
(2MB)
Date of publication of this fulltext: 08 Feb 2021 11:41

This publication is part of the DEAL contract with Springer.


Abstract

Pharmacologic approaches for the treatment of atrial arrhythmias are limited due to side effects and low efficacy. Thus, the identification of new antiarrhythmic targets is of clinical interest. Recent genome studies suggested an involvement of SCN10A sodium channels (Na(V)1.8) in atrial electrophysiology. This study investigated the role and involvement of Na(V)1.8 (SCN10A) in arrhythmia ...

plus


Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons