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Identification of FoxP circuits involved in locomotion and object fixation in Drosophila

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Palazzo, Ottavia ; Rass, Mathias ; Brembs, Björn
License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 18 Feb 2021 09:35


The FoxP family of transcription factors is necessary for operant self-learning, an evolutionary conserved form of motor learning. The expression pattern, molecular function and mechanisms of action of the Drosophila FoxP orthologue remain to be elucidated. By editing the genomic locus of FoxP with CRISPR/Cas9, we find that the three different FoxP isoforms are expressed in neurons, but not in ...


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