Validation of an apoptosis assay for extracorporeal photopheresis

URN to cite this document:: urn:nbn:de:bvb:355-epub-451833
DOI to cite this document:: 10.5283/epub.45183

Hähnel, Viola

; Dormann, Frauke ; Kronenberg, Katharina ; Hutchinson, James A.

; Burkhardt, Ralph

; Ahrens, Norbert

Preview

License: Creative Commons Attribution Non-commercial No Derivatives 4.0
PDF - Published Version
(2MB)

Date of publication of this fulltext: 11 Mar 2021 10:33

Alternative links to fulltext:DOI Publisher

Details

Preview

Export bibliographical data

Abstract

Objectives This validation study investigated a flow cytometric apoptosis assay according to good manufacturing practice (GMP). Background Extracorporeal photopheresis (ECP) is a treatment for various immunological diseases and cutaneous T‐cell lymphomas. It is based on the induction of apoptosis by 8‐methoxypsoralene and ultraviolet A light. The quantification of apoptosis is therefore ...