Zusammenfassung
Objectives: The efficacy of an anti-infective drug is influenced by its protein binding (PB), since only the free fraction is active. We hypothesized that PB may vary in vitro and in vivo, and used clindamycin, a drug with high and concentration-dependent PB to investigate this hypothesis. Methods: Six healthy volunteers received a single intravenous infusion of clindamycin 900 mg. Antibiotic ...
Nur für Besitzer und Autoren: Kontrollseite des Eintrags
Altmetric