Distribution of Gold Nanoparticles in the Anterior Chamber of the Eye after Intracameral Injection for Glaucoma Therapy

URN to cite this document:: urn:nbn:de:bvb:355-epub-458530
DOI to cite this document:: 10.5283/epub.45853

Breunig, Miriam

; Sonntag, Tobias ; Froemel, Franziska ; Stamer, W. Daniel ; Ohlmann, Andreas ; Fuchshofer, Rudolf

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Date of publication of this fulltext: 25 Jun 2021 16:47

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Abstract

In glaucoma therapy, nanoparticles (NPs) are a favorable tool for delivering drugs to the outflow tissues of the anterior chamber of the eye where disease development and progression take place. In this context, a prerequisite is an efficient enrichment of NPs in the trabecular meshwork with minimal accumulation in off-target tissues such as the cornea, lens, iris and ciliary body. We evaluated ...