Association of mitochondrial DNA copy number with metabolic syndrome and type 2 diabetes in 14 176 individuals

URN to cite this document:: urn:nbn:de:bvb:355-epub-458944
DOI to cite this document:: 10.5283/epub.45894

Fazzini, F. ; Lamina, C. ; Raftopoulou, A. ; Koller, A. ; Fuchsberger, C. ; Pattaro, C. ; Del Greco, F. M. ; Döttelmayer, P. ; Fendt, L. ; Fritz, J. ; Meiselbach, H. ; Schönherr, S. ; Forer, L. ; Weissensteiner, H. ; Pramstaller, P. P. ; Eckardt, K.‐U. ; Hicks, A. A. ; Kronenberg, Florian

; Oefner, Peter

; Gronwald, Wolfram

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Date of publication of this fulltext: 31 May 2021 09:55

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Abstract

Background Mitochondria play an important role in cellular metabolism, and their dysfunction is postulated to be involved in metabolic disturbances. Mitochondrial DNA is present in multiple copies per cell. The quantification of mitochondrial DNA copy number (mtDNA-CN) might be used to assess mitochondrial dysfunction. Objectives We aimed to investigate the cross-sectional association of ...