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Impact of Leptin on Periodontal Ligament Fibroblasts during Mechanical Strain

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Schröder, Agnes ; Meyer, Andrea ; Spanier, Gerrit ; Damanaki, Anna ; Paddenberg, Eva ; Proff, Peter ; Kirschneck, Christian
License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 05 Nov 2021 16:41


Orthodontic treatment to correct dental malocclusions leads to the formation of pressure zones in the periodontal ligament resulting in a sterile inflammatory reaction, which is mediated by periodontal ligament fibroblasts (PDLF). Leptin levels are elevated in obesity and chronic inflammatory responses. In view of the increasing number of orthodontic patients with these conditions, insights into ...


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