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Impact of Leptin on Periodontal Ligament Fibroblasts during Mechanical Strain

URN to cite this document:
urn:nbn:de:bvb:355-epub-460001
DOI to cite this document:
10.5283/epub.46000
Schröder, Agnes ; Meyer, Andrea ; Spanier, Gerrit ; Damanaki, Anna ; Paddenberg, Eva ; Proff, Peter ; Kirschneck, Christian
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License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 05 Nov 2021 16:41



Abstract

Orthodontic treatment to correct dental malocclusions leads to the formation of pressure zones in the periodontal ligament resulting in a sterile inflammatory reaction, which is mediated by periodontal ligament fibroblasts (PDLF). Leptin levels are elevated in obesity and chronic inflammatory responses. In view of the increasing number of orthodontic patients with these conditions, insights into ...

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