| Lizenz: Creative Commons Namensnennung 4.0 International PDF - Veröffentlichte Version (8MB) |
- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-460605
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.46060
Zusammenfassung
Activation of the Ca2+ activated Cl- channel TMEM16A is proposed as a treatment in inflammatory airway disease. It is assumed that activation of TMEM16A will induce electrolyte secretion, and thus reduce airway mucus plugging and improve mucociliary clearance. A benefit of activation of TMEM16A was shown in vitro and in studies in sheep, but others reported an increase in mucus production and ...
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