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NMR resonance assignments for the SAM/SAH-binding riboswitch RNA bound to S-adenosylhomocysteine

Weickhmann, A. Katharina ; Keller, Heiko ; Duchardt-Ferner, Elke ; Strebitzer, Elisabeth ; Juen, Michael A. ; Kremser, Johannes ; Wurm, Jan Philip ; Kreutz, Christoph ; Wöhnert, Jens



Abstract

Riboswitches are structured RNA elements in the 5-untranslated regions of bacterial mRNAs that are able to control the transcription or translation of these mRNAs in response to the specific binding of small molecules such as certain metabolites. Riboswitches that bind with high specificity to either S-adenosylmethionine (SAM) or S-adenosylhomocysteine (SAH) are widespread in bacteria. Based on ...

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