Mohamed, Belal A. 
; Hartmann, Nico ; Tirilomis, Petros ; Sekeres, Karolina ; Li, Wener ; Neef, Stefan ; Richter, Claudia ; Zeisberg, Elisabeth M. ; Kattner, Lars ; Didié, Michael ; Guan, Kaomei ; Schmitto, Jan D. ; Lehnart, Stephan E. ; Luther, Stefan ; Voigt, Niels ; Seidler, Tim ; Sossalla, Samuel ; Hasenfuss, Gerd ; Toischer, Karl
; Hartmann, Nico ; Tirilomis, Petros ; Sekeres, Karolina ; Li, Wener ; Neef, Stefan ; Richter, Claudia ; Zeisberg, Elisabeth M. ; Kattner, Lars ; Didié, Michael ; Guan, Kaomei ; Schmitto, Jan D. ; Lehnart, Stephan E. ; Luther, Stefan ; Voigt, Niels ; Seidler, Tim ; Sossalla, Samuel ; Hasenfuss, Gerd ; Toischer, Karl 
Zusammenfassung
Increased sarcoplasmic reticulum (SR) Ca2+ leak via the cardiac ryanodine receptor (RyR2) has been suggested to play a mechanistic role in the development of heart failure (HF) and cardiac arrhythmia. Mice treated with a selective RyR2 stabilizer, rycal S36, showed normalization of SR Ca2+ leak and improved survival in pressure overload (PO) and myocardial infarction (MI) models. The development ...
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