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Long-term expression of glomerular genes in diabetic nephropathy

Chittka, Dominik ; Banas, Bernhard ; Lennartz, Laura ; Putz, Franz Josef ; Eidenschink, Kathrin ; Beck, Sebastian ; Stempfl, Thomas ; Moehle, Christoph ; Reichelt-Wurm, Simone ; Banas, Miriam C.


Background. Although diabetic nephropathy (DN) is the most common cause for end-stage renal disease in western societies, its pathogenesis still remains largely unclear. A different gene pattern of diabetic and healthy kidney cells is one of the probable explanations. Numerous signalling pathways have emerged as important pathophysiological mechanisms for diabetes-induced renal injury. Methods. ...


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