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Biomarker-guided Intervention to Prevent Acute Kidney Injury After Major Surgery

Göcze, Ivan ; Jauch, Dominik ; Götz, Markus ; Kennedy, Pascal ; Jung, Bettina ; Zeman, Florian ; Gnewuch, Carsten ; Graf, Bernhard M. ; Gnann, Wolfgang ; Banas, Bernhard ; Bein, Thomas ; Schlitt, Hans J. ; Bergler, Tobias


Objective: To determine the impact of renal biomarker-guided implementation of the Kidney Disease Improving Global Outcomes (KDIGO) care bundle on the incidence of acute kidney injury (AKI) after major noncardiac surgery in a single-center unblinded randomized clinical trial. Background: Early optimization of volume status and discontinuation of nephrotoxic medication before the occurrence of AKI ...


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